Contact Information

Mailing Address: School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, 219 Ningliu Road, Nanjing, Jiangsu, 210044, P.R.China

Email: yingli@nuist.edu.cn & yingliubc@gmail.com

Education

09/2006-01/2012         Ph.D, Organic Chemistry
Applying Aryltrifluoroborates as PET Imaging Agents
Department of Chemistry, the University of British Columbia, Canada
Supervisor: Dr. David M. Perrin 

09/2003-06/2006         M.Sc., Organic Chemistry
Synthesis of Nuclease Model Compounds and Research on Their Interaction with DNA
School of Chemistry and Chemical Engineering, Nanjing University, China
Supervisor: Guoyuan Lu 

09/1999-07/2003         B.Sc., Applied Chemistry
School of Chemistry and Chemical Engineering, Nanjing University, China
Supervisor: Guoyuan Lu

Working Experiences

08/2014-date               Professor

                                    School of Chemistry and Materials, Nanjing University of Information Science & Technology

07/2014-07/2019         Professor

                                   Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution Control, College of Environmental    

                                   Science & Engineering, Nanjing University of Information Science & Technology

04/2013- 07/2014        Faculty

                                    Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution Control, College of Environmental 

                                    Science & Engineering, Nanjing University of Information Science & Technology

10/2012-12/2014         Postdoctoral fellow

                                    Department of Physics, Nanjing University

                                    Supervisor: Dr. Wei Wang

01/2012-06/2012         Postdoctoral fellow
                                    Department of Chemistry, the University of British Columbia, Canada
                                    Supervisor: Dr. David M. Perrin

Fundings

1.                 Jiangsu PhD gathering scheme（2014, 150 k）

2.                 the Technology Foundation for Selected Overseas Chinese Scholar

3.                 The Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, China

4.                 Natural Science Foundation of China 

5.                 General Financial Grant from the China Postdoctoral Science Foundation

Professional Societies

Member, Chinese Chemical Society (2016-2021)

Member, Canadian Society of Chemistry (2014)

Member, Canadian Society of Chemistry (2011)

Member, Canadian Society of Chemistry (2010)

Member, Canadian Society of Chemistry (2008)

Publications

1. Yingjie Xu^#, Xin Wu^#, Shuyi Wang, Changzhou Yang, Ying Li*, Yi Cao*, Hydroxyapatite nanoparticle-crosslinked peptide hydrogels for three-dimensional culture and differentiation of MC3T3-E1 osteoblasts, Journal of Biomedical Nanotechnology, 2019, manuscript accepted.

2. Wenting Yu, Wenxu Sun, Qiyang Fan, Bin Xue, Yiran Li, Meng Qin, Ying Li, Bin  Chen*, Wei Wang*, Yi Cao*, Tuning of the dynamics of metal ion crosslinked hydrogels by network structures, Soft Matter, 2019, 15(22), 4423-4427. (DOI: 10.1039/C9SM00768G)

3. Liang Zeng^#, Mingming Song^#, Jie Gu, Zhengyu Xu, Bin Xue *, Ying Li *, Yi Cao*, A Highly stretchable, tough and fast self-healing hydrogel based on peptide-metal ion coordination, Biomimetics, 2019, 4(2), 36.

4. Bing Li^#, Xin Wang^#, Ying Li, Arja Paananene, Geza R. Szilvay, Meng Qin, Wei Wang*, Yi Cao*, Single-Molecule Force Spectroscopy Reveals Self-Assembly Enhanced Surface Binding of Hydrophobins, Chemistry-A European Journal, 2018, 24(37), 9224-9228.

5. Ying Li, Yi Cao*, The Physical Chemistry for the Self-assembly of Peptide Hydrogels, Chinese Journal of Polymer Science, 2018,36(3), 366-378.

6. Xin Wu, Wenmao Huang, Wen-Hao Wu, Bin Xue, Dongfang Xiang, Ying Li, Meng Qin, Fei Sun, Wei Wang*, Wen-Bin Zhang*, Yi Cao*, Reversible hydrogels with tunable mechanical properties for optically controlling cell migration, Nano Research, 2018, 11(10), 5556-5565. 
   (DOI: 10.1007/s12274-017-1890-y)

7. Ying Li^#, Chao Liang^#, Ling Gao, Shiyu Li, Yizhe Zhang, Jiang Zhang，Yi Cao^*, Hidden Complexity of Synergistic Roles of Dopa and Lysine for Strong Wet Adhesion, Materials Chemistry Frontiers, 2017, 1(12), 2664-2668.

8. Yifan Xia^#, Bin Xue^#*, Meng Qin, Yi Cao, Ying Li*, Wei Wang*, Printable Fluorescent Hydrogels Based on Self-Assembling Peptides, Scientific Reports, 2017, 7, 9691. (DOI: 10.1038/s41598-017-10162-y)

9. Yiran Li, Tiankuo Wang, Lei Xia, Lei Wang, Meng Qin, Ying Li*, Wei Wang*, Yi Cao*, Single molecule study of the synergistic effects of positive charges and Dopa for wet adhesion, Journal of Materials Chemistry B, 2017, 5, 4416-4420.(DOI: 10.1039/C7TB00131B)

10. Wenmao Huang, Meng Qin, Ying Li*, Yi Cao*, Wei Wang*, Dimerization of Cell-Adhesion Molecules Can Increase Their Binding Strength, Langmuir2017,33(6), 1398-1404. (DOI: 10.1021/acs.langmuir.6b04396)

11. Bin Xue, Meng Qin, Tiankuo Wang, Junhua Wu, Dongjun Luo, Qing Jiang, Ying Li*, Yi Cao*, Wei Wang*, Electrically controllable actuators based on supramolecular peptide hydrogel, Advanced Functional Materials, 2016, 26(48),9053-9062. (DOI: 10.1002/adfm.201603947)

12. Wenxu Sun^#, Bin Xue^#, Ying Li, Meng Qin, Junyi Wu, Ke Lu, Junhua Wu, Yi Cao*, Qing Jiang*, Wei Wang*, Polymer-Supramolecular Polymer Double-Network Hydrogel, Advanced Functional Materials, 2016, 26(48),9044-9052. (DOI: 10.1002/adfm.201603512)

13. Daniel Walker, Ying Li, Aron Roxin, Paul Schaffer, Michael J. Adam, David M. Perrin, Facile synthesis and ¹⁸F-radiolabeling of α₄β₁-specific LLP2A-aryltrifluoroborate peptidomimetic conjugates,Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 5126-5131.

14. Ying Li*, Lei Wang, A small peptide hydrogel for organic dye removal, ChemistryLetters, 2016, 45,1253-1255. (DOI:10.1246/cl.160597)

15. Bin Xue, Meng Qin, Junhua Wu, Dongjun Luo, Qing Jiang, Ying Li*, Yi Cao*,and Wei Wang*, Electroresponsive Supramolecular Graphene Oxide Hydrogels for Active Bacteria Adsorption and Removal, ACS Applied Materials & Interfaces,2016,8(24), 15120−15127

16. Wei Cheng, Ying Li*, Peptide Hydrogelation Triggered by Enzymatic Induced pH Switch, Science China-Physics, Mechanics & Astronomy, 2016, 59, 678711. 

17. Chenyu Wang, Xinyi Cui*, Ying Li*, Hongbo Li, Lei Huang, Jun Bi, Jun Luo, Lena Q. Ma, Wei Zhou, Yi Cao, Baigeng Wang, Feng Miao*,A label-free and portable graphene FET aptasensor for children blood lead detection, Scientific Reports,2016, 6, 21711 (DOI: 10.1038/srep21711).

18. Li, Y.^#*, Sun, Y.^#, Qing, M., Cao, Y.*, Wang, W.*, Mechanics of single peptide hydrogelator fibrils, Nanoscale, 2015, 7(13), 5638-5642.

19. Liu, Z., Chao, D., Li, Y., Ting, R., Oh, J., Perrin, D.M.*, From Minutes to Years: Predicting Organotrifluoroborate Solvolysis Rates, Chemistry-A European Journal,2015, 21(10), 3924-3928.

20. Liu, Z., Li, Y., Ting, R., Perrin, D.M.*, Designing kinetically stable aryltrifluoroborates as ¹⁸F-capture agents for PET imaging, Journal of Physical Organic Chemistry, 2015, 28(3), 210-214.

21. Wu, J., Chen, A., Qin, M., Huang, R., Zhang, G., Xue, B., Gao, X., Li, Y.*,Cao, Y.*, Wang, W.*, Hierarchical construction of a mechanically stable peptide-graphene oxide hybrid hydrogel for drug delivery and pulsatile triggered release in vivo, Nanoscale,2015, 7(5), 1655-1660.

22. Li, Y., Qin, M., Li, Y., Cao, Y.*,Wang, W.*, Single molecule evidences for the adaptive binding of DOPA to different wet surfaces, Langmuir, 2014, 30(15), 4358-4366.

23. Xue, B., Li, Y., Qin, M., Cao, Y.*, Wang, W.*, Integrated artificial photosynthesis system based on peptide nanotubes, Nanoscale2014, 6(14), 7832-7837.

24. Li, Y., Qin, M., Cao, Y.*, Wang, W.*, Designing the mechanical properties of peptide-based supramolecular hydrogels for biomedical applications, Science China-Physics, Mechanics & Astronomy, 2014, 57(5), 849-858.

25. Li, Y.*, ¹⁸F-Labeling techniques for positron emission tomography,Science China-Chemistry, 2013, 56(12), 1682-1692.

26. Xie, J., Li, Y., Cao, Y., Xu, C., Xia, M., Qin, M.*, Wei, J., Wang, W.*, Photo synthesis of protein-based drug delivery nanoparticles for active tumor targeting,Biomaterials Science, 2013,1(12), 1216-1222.  

27. Ding, Y.^‡, Li, Y.^‡*, Qin, M.*, Cao, Y., Wang, W.*, Photo-cross-linking approach towards engineering small tyrosine-containing peptide hydrogels of enhanced mechanical stability, Langmuir,2013, 29(23), 13299-13306.

28. Li, Y., Schaffer, P., Perrin, D. M.*, Dual isotope labeling: Conjugation of ³²P-oligonucleotides with ¹⁸F-aryltrifluoroborate via copper(I) catalyzed cycloaddition, Bioorganic and Medicinal Chemistry Letters, 2013,23(23)6313-6316.

29. Li, Y., Liu, Z., Lozada, J., Wong, M.Q., Lin, K.-S., Yapp, D., Perrin, D.M.*, Single step ¹⁸F-labeling of dimeric cycloRGD for functional PET imaging of tumors in mice, Nuclear Medicine and Biology,2013, 40(8), 959-966.

30. Wu, L.‡, Li, Y.‡,Yang Y., Qin, M.*,Deciphering Structural and Functional Roles of Disulfide Bonds in Decorsin, Science China- Chemistry, 2013, 56(10), 1485-1492.

31. Li, Y.*, Ding, Y., Qin, M.*, Cao, Y., Wang, W.*, An enzyme-assisted nanoparticle crosslinking approach to enhance the mechanical strength of peptide-based supramolecular hydrogels peptide-based supramolecular hydrogels, Chemical Communications, 2013,49(77), 8653-8655.

32. Liu, Z., Li, Y., Lozada, J., Wong, M.Q., Greene, J., Lin, K.-S., Yapp, D., Perrin, D.M.*, Kit-like ¹⁸F-labeling of RGD-¹⁹F-aryltrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivotumor imaging, Nuclear Medicine and Biology, 2013, 40(6), 841-849.

33. Ding, B.^‡, Li, Y.^‡*, Qin, M., Ding, Y., Cao, Y., Wang, W.*, Two approaches for the engineering of homogeneous small-molecule hydrogels, Soft Matter, 2013, 9(18), 4672-4680.

34. Liu, Z., Li, Y., Lozada, J., Schaffer, P., Adam, M. J., Ruth, T. J., Perrin, D. M.*, Stoichiometric leverage: rapid ¹⁸F-aryltrifluoroborate radiosynthesis at high specific activity for click conjugation, Angewandte Chemie International Edition,2013, 52(8), 2303-2307.

35. Li, Y., Liu, Z., Harwig, C.W., Pourghiasian, M., Lau, J., Lin, K.-S, Schaffer, P., Benard, F., Perrin, D. M.*, ¹⁸F-Click labeling of a bombesin antagonist with an alkyne-¹⁸F-ArBF₃^-:in vivoPET imaging of tumors expressing the GRP-receptor, American Journal of Nuclear Medicine and Molecular Imaging, 2013, 3(1), 57-70.

36. Li. Y., Guo, J., Tang, S., Lang, L., Chen, X., Perrin, D.M.*, One-step and one-pot-two-step radiosynthesis of cyclo-RGD-[¹⁸F]-aryltrifluoroborate conjugates for functional imaging, American Journal of Nuclear Medicine and Molecular Imaging, 2013,3(1), 44-56.

37. Liu, Z., Li, Y., Lozada J., Pan, J., Lin, K.-S., Schaffer, P., Perrin, D.M.*, Rapid, one-step, high yielding ¹⁸F-labeling of an aryltrifluoroborate bioconjugate by isotope exchange at very high specific activity, Journal of Labelled Compounds and Radiopharmaceuticals, 2012,55(14), 491-496.

38. Li, Y., Ting, R., Harwig, C.W., auf dem Keller, U., Bellac, C.L., Lange, P.F., Inkster, J.A.H., Schaffer, P., Adam, M.J., Ruth, T.J., Overall, C.M., Perrin, D.M.*, Towards kit-like ¹⁸F-labeling of marimastat, a noncovalent inhibitor drug for in vivoPET imaging cancer associated matrix metalloproteases, MedChemComm, 2011, 2(10),942-949. (Cover Issue)

39. Auf dem Keller, U., Bellac, C.L., Li, Y., Lou, Y., Lange, P.F., Ting, R., Harwig, C., Kappelhoff, R., Dedhar, S., Adam, M.J., Ruth, T.J., Bénard, F., Perrin, D.M., Overall, C.M.*,Novel matrix metalloproteinase inhibitor [¹⁸F]marimastat-aryltrifluoroborate as a probe for in vivopositron emission tomography imaging in cancer, Cancer Research, 2010, 70(19), 7562-7569.

40. Li, Y., Asadi, A., Perrin, D.M.*, Hydrolytic stability of nitrogenous- heteroaryltrifluoroborates under aqueous conditions at near neutral pH, Journal of Fluorine Chemistry, 2009, 130(4), 377-382.

41. Zhang, J.-J., Shao, Y., Wei, L., Li, Y., Sheng, X., Liu, F., Lu, G.-Y.*, Design of artificial nucleases and studies of their interaction with DNA, Science in China Series B-Chemistry, 2009, 52(4),402-414.  

42. Shao, Y., Sheng, X., Li, Y., Jia, Z.-L., Zhang, J.-J., Liu, F., Lu, G.-Y.*, DNA binding and cleaving activity of the new cleft molecule N,N'-bis(guanidinoethyl)-2,6-pyridinedicarboxamide in the absence or in the presence of copper(II), Bioconjugate Chemistry, 2008, 19(9), 1840-1848. 

43. Ting, R., Harwig, C.W., Lo, J., Li, Y., Adam, M.J., Ruth, T.J., Perrin, D.M.*, Substituent effects on aryltrifluoroborate solvolysis in water: implications for Suzuki-Miyaura coupling and the design of stable ¹⁸F-labeled aryltrifluoroborates for use in PET imaging, Journal of Organic Chemistry, 2008, 73(12), 4662-4670.

44. Li, Y., Sheng, X., Shao, Y., Lu, G.-Y.*, DNA cleavage promoted by Cu²⁺complex of N,N'-bis(2-aminoethyl)-2,6-pyridinedicarboxamide,Chinese Journal of Chemistry, 2007, 25(7), 937-947.

45. Li, Y., Lu, X.-M., Sheng, X., Lu, G.-Y.*, Shao, Y., DNA cleavage promoted by Cu²⁺complex of cyclen containing pyridine subunit, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007,59(1-2), 91-98.

46. Shi, Z.-W., Li, Y., Lu, G.-Y.*, Zhang, C.-Z., Liu, F., Synthesis and nonlinear optical properties of chromophores with 1,8-dimethoxy-9,10–dihydro anthracene and ring-locked triene, Chinese Journal of Chemistry,2007, 25(1), 116-120. 

47. Lu, G.-Y.*, Shi, Z.-W., Zhang, C.-Z., Li, Y.Preparation of 9,10-dihydroanthracene chromophore compounds,Faming Zhuanli Shenqing Gongkai Shuomingshu,2005, CN1621452, 15pp.

48. Shi, Z.-W., Li, Y., Lu, G.-Y.*, Synthesis of 1,8-dihydroxy-9,10- dihydroanthracene,Chemical Journal of Chinese Universities, 2005, 26(4),667-670. 

49. Shi, Z.-W., Li, Y.-Z., Li, Y., Lu, G.-Y.*, Liu, S.-H., 1,1',8,8'-Tetramethoxy-10,10'-bianthrone, Acta Crystallographical Section E-Structure Reports online, 2004,E60, o2275-o2277. 

50. Guo, X., Lu, G.-Y.*, Li, Y., Interaction between calix[4]arene derivative bearing adenino units and complementary nucleosides at the air-water interface, Thin Solid Films, 2004,460(1-2), 264-268.