智慧医疗研究院（点击访问网站）

主要研究方向：医学图像智能分析，模式识别，MRI成像，PET分子影像

研究内容：

*图像超体素分割：将组织过分割为内部功能一致、空间连续、形态致密的超体素（Superpixel/Supervoxel），超体素反映了组织和病理体素值的内在统计分布模式，可用于数据降维、感兴趣区（ROI）分析等。

   

        基于白质超体素分割的统计分析（Ref）                 基于皮层超体素分割的纤维连接密度分析（Ref）

*脑网络分析：使用图论方法分析大脑结构连接（DTI影像）和功能连接（fMRI影像），研究疾病、衰老和发育过程中脑网络拓扑属性和局部连接的改变。

                                 功能脑网络分析认知水平下降（Ref）

*脑模板构建：基于组水平配准方法构建人群的平均脑影像，即脑模板，可显著提高特定人群（如儿童和老年人）脑影像的空间标准化精度。

   

             儿童脑模板（Ref）                                                 PET脑模板空间标准化及定量分析综述（Ref）

发表论文：

2024年

[1] Lening Li, Teng Zhang, Fan Lin, Yuting Li, MS Wong, "Automated 3D Cobb Angle Measurement Using U-Net in CT Images of Preoperative Scoliosis Patients", Journal of Imaging Informatics in Medicine, https://doi.org/10.1007/s10278-024-01211-w

[2] Weilang Wang, Shuhang Zhang, Binyan Zhong, Wu Cai, Lei Gao, Binrong Li, Dandan Yao, Yuan Zhao, Ziying Sun, Shuwei Zhou, Teng Zhang, Xunjun Chen, Shenghong Ju, Yuan-Cheng Wang, " Dynamic changes of radiological and radiomics patterns based on MRI in viable hepatocellular carcinoma after transarterial chemoembolization", Abdominal Radiology, https://doi.org/10.1007/s00261-024-04676-z

[3] Yuting Li, Teng Zhang, Chao Wang, Leiyu Geng, Tingting Liu, Tong Lu, Shenghong Ju, "The Impact of Sleep Disorders on Glymphatic Function in Parkinson’s Disease Using Diffusion Tensor MRI", Academic Radiology, https://doi.org/10.1016/j.acra.2024.11.030

2023年

[1] Qi Li, Zhenghao Zhou, Yukun Chen, Jieyu Yu, Hao Zhang, Yinghao Meng, Mengmeng Zhu, Na Li, Jian Zhou, Fang Liu, Xu Fang, Jing Li, Tiegong Wang, Jianping Lu, Teng Zhang, Jun Xu, Chengwei Shao, Yun Bian, "Fully automated magnetic resonance imaging-based radiomics analysis for differentiating pancreatic adenosquamous carcinoma from pancreatic ductal adenocarcinoma", Abdominal Radiology, 48(6): 2074-2084, https://doi.org/10.1007/s00261-023-03801-8

[2] Zhenghao Zhou, Tianyi Xia, Teng Zhang, Mingyang Du, Jiarui Zhong, Yunzhi Huang, Kai Xuan, Geyang Xu, Zhuo Wan, Shenghong Ju, Jun Xu, "Prediction of preoperative microvascular invasion by dynamic radiomic analysis based on contrast-enhanced computed tomography", Abdominal Radiology, 49:611–624, https://doi.org/10.1007/s00261-023-04102-w

2022年

[1] Teng Zhang, Shuang Wu, Xiaohui Zhang, Yiwu Dai, Anxin Wang, Hong Zhang, Mei Tian, “Spatial normalization and quantification approaches of PET imaging for neurological disorders.” European Journal of Nuclear Medicine and Molecular Imaging, 49:3809-3829 (2022). https://doi.org/10.1007/s00259-022-05809-6

[2] Yuting Li#, Teng Zhang#, Jianhua Feng#, Shufang Qian, Shuang Wu, Rui Zhou, Jing Wang, Guo Sa, Xiawan Wang, Lina Li, Feng Chen, Hong Yang, Hong Zhang, Mei Tian,  “Processing speed dysfunction is associated with functional corticostriatal circuit alternations in childhood epilepsy with centrotemporal spikes: a PET and fMRI study.” European Journal of Nuclear Medicine and Molecular Imaging, 49:3186-3196 (2022). https://doi.org/10.1007/s00259-022-05740-w

[3] Kai Liu#, Xiaopeng Wang#, Teng Zhang, Wei Wang, Ruohan Li, Li Lu, Yanjia Deng, Kai Xu, Timothy Kwok,  “Cortical Short-Range Fiber Connectivity and Its Association with Deep Brain White Matter Hyperintensities in Older Diabetic People with Low Serum Vitamin B12”, Frontiers in Aging Neuroscience (2022), https://doi.org/10.3389/fnagi.2022.754997

[4] Teng Zhang#, Yuting Li#, Shuilin Zhao, Yuanfan Xu, Xiaohui Zhang, Shuang Wu, Xiaofeng Dou, Congcong Yu, Jianhua Feng, Yao Ding, Junming Zhu, Zexin Chen, Hong Zhang, Mei Tian, “High-resolution pediatric age–specific 18F-FDG PET template: a pilot study in epileptogenic focus localization.” European Journal of Nuclear Medicine and Molecular Imaging, 49: 1560-1573 (2022). https://doi.org/10.1007/s00259-021-05611-w

[5] Xiaohui Zhang#, Lin Chen#, Han Jiang#, Xuexin He, Liu Feng, Miaoqi Ni, Mindi Ma, Jing Wang, Teng Zhang, Shuang Wu, Rui Zhou, Chentao jin, Kai Zhang, Wenbin Qian, Zexin Chen, Cheng Zhuo, Hong Zhang, Mei Tian, “A novel analytic approach for outcome prediction in diffuse large B‑cell lymphoma by [18F]FDG PET/CT.” European Journal of Nuclear Medicine and Molecular Imaging, 49: 1298-1310 (2022). https://doi.org/10.1007/s00259-021-05572-0

2021年

[1] Yuting Li#, Jianhua Feng#, Teng Zhang, Kexin Shi, Yao Ding, Xiaohui Zhang, Chentao Jin, Jiayue Pan, Le Xue, Yi Liao, Xiawan Wang, Cheng Zhuo, Hong Zhang, Mei Tian, “Brain metabolic characteristics distinguishing typical and atypical benign epilepsy with centro-temporal spikes.” European Radiology, 31: 9335-9345 (2021). https://doi.org/10.1007/s00330-021-08051-0

[2] Qinming Zhang#, Yi Liao#, Xiawan Wang#, Teng Zhang#, Jianhua Feng#, Jianing Deng, Kexin Shi, Lin Chen, Liu Feng, Mindi Ma, Le Xue, Haifeng Hou, Xiaofeng Dou, Congcong Yu, Lei Ren, Yao Ding, Yufei Chen, Shuang Wu, Zexin Chen, Hong Zhang, Cheng Zhuo, Mei Tian, “A deep learning framework for 18F-FDG PET imaging diagnosis in pediatric patients with temporal lobe epilepsy.” European Journal of Nuclear Medicine and Molecular Imaging, 48: 2476–2485 (2021). https://doi.org/10.1007/s00259-020-05108-y

2020年之前

[1] Steve CN Hui, Teng Zhang, Lin Shi, Defeng Wang, Chei-Bing Ip, and Winnie CW Chu. “Automated Segmentation of Abdominal Subcutaneous Adipose Tissue and Visceral Adipose Tissue in Obese Adolescent in MRI.” Magnetic Resonance Imaging, 45: 97-104 (2018). https://doi.org/10.1016/j.mri.2017.09.016

[2] Kai Liu#, Teng Zhang#, Winnie CW Chu, Vincent CT Mok, Defeng Wang, and Lin Shi. “Group Comparison of Cortical Fiber Connectivity Map: An Application between Post-stroke Patients and Healthy Controls.” Neuroscience, 344: 15-24 (2017). https://doi.org/10.1016/j.neuroscience.2016.12.026

[3] Steve CN Hui, Jacky KL Ko, Teng Zhang, Lin Shi, David KW Yeung, Defeng Wang, Queenie Chan, and Winnie CW Chu. “Quantification of Brown and White Adipose Tissue based on Gaussian Mixture Model using Water-fat and T2* MRI in Adolescents.” Journal of Magnetic Resonance Imaging, 46, no. 3: 758-768 (2017). https://doi.org/10.1002/jmri.25632

[4] Teng Zhang, Defeng Wang, Qing Zhang, Jianlin Wu, Jian Lv, and Lin Shi. “Supervoxel-based Statistical Analysis of Diffusion Tensor Imaging in Schizotypal Personality Disorder.” NeuroImage, 163: 368-378 (2017). https://doi.org/10.1016/j.neuroimage.2017.07.026

[5] Kai Liu, Teng Zhang, Qing Zhang, Yueji Sun, Jianlin Wu, Yi Lei, Winnie CW Chu, Vincent CT Mok, Defeng Wang, and Lin Shi. “Characterization of the Fiber Connectivity Profile of the Cerebral Cortex in Schizotypal Personality Disorder: A Pilot Study.” Frontiers in Psychology, 7: 809 (2016). https://doi.org/10.3389/fpsyg.2016.00809

2013.8 -- 2017.11
香港中文大学       影像及介入放射学       博士研究生毕业       哲学博士学位

2010.9 -- 2013.6
浙江大学       电气工程       硕士研究生毕业       工程硕士专业学位

2006.9 -- 2010.7
浙江大学       电子信息工程       大学本科       工学学士学位

2018.8 -- 2021.11

浙江大学      PET中心      博士后

2017.12 -- 2018.7

香港中文大学      影像及放射学系      研究助理/博士后

医学图像分析

模式识别