高凡,女,1992年11月出生,中共党员。2011-2015年就读于湖南大学化学化工学院(本科),2015-2020年就读于武汉大学化学与分子科学学院(硕博连读),2020年8月起,加盟南京信息工程大学。主要研究方向为生物医用纳米材料,致力于为人类重大疾病的诊断和治疗提供新策略。先后以一作或共一作在Adv. Mater., Small,Sci. China Chem. ,Nature Communication,Adv. Funct. Mater. 以及ACS Nano等国际高水平学术期刊上发表SCI收录学术论文13篇。
科研成果:
1. Gao F, Dong JH, Xue C, An L, Zhang J, Wang WJ, Ou CJ, Dong XC. Nanomaterials-involved strategies for reversing the immunosuppressive factors and improving antitumor immunotherapy. Nano today 2023, 50, 101831.
2. Gao F, Xue C, Zhang T, Zhang L, Zhu GY, Ou CJ, Zhang YZ, Dong XC. MXenes-based functional platforms for tumor therapy. Adv. Mater. 2023, 35, 2302559.
3. Gao F, Xue C, Dong JH, Lu XX, Yang N, Ou CJ, Mou XZ, Zhang YZ, Dong XC. Tumor microenvironment-induced drug depository for persistent antitumor chemotherapy and immune activation. Small 2023, 2307736.
4. Gao F, Dong JH, Xue C, Lu XX, Cai Y, Tang ZY, Ou CJ. Tumor-targeting multiple metabolic regulations for bursting antitumor efficacy of chemodynamic therapy. Small 2024, 2310248.
5. Lu XX, Xue C, Dong JH, Zhang ZY, Gao F*. Nanoplatform-based strategies for enhancing the lethality of current antitumor PDT. J. Mater. Chem. B, 2024, accepted.
6. Gao F#, Tang Y#, Liu WL, Zou MZ, Huang C, Liu CJ, Zhang XZ. Intra/extracellular lactic acid exhaustion for synergistic metabolic therapy and immunotherapy of tumors. Adv. Mater. 2019, 31, 1904639.
7. Gao F, Zhang C, Qiu WX, Dong X, Zheng DW, Wu W, Zhang XZ. PD-1 blockade for improving the antitumor efficiency of polymer–doxorubicin nanoprodrug. Small 2018, 14, 1802403.
8. Gao F#, Cheng Q#, Liu MD, Rong L, Liu CJ, Zhang XZ. Local T regulatory cells depletion by an integrated nanodrug system for efficient chem-immunotherapy of tumor. Sci. China Chem. 2019, 62, 1230.
9. Zheng DW#, Gao F#, Cheng Q, Bao P, Dong X, Fan JX, Song W, Zeng X, Cheng SX, Zhang XZ. Vaccine comprised nanosystem for initiating innate immunity and improving tumor immunotherapy. Nat. Commun. 2020, 11, 1985.
10. Zhang C#, Gao F#, Wu W, Qiu WX, Zhang L, Li RQ, Zhuang ZN, Yu WY, Cheng H, Zhang XZ. Enzyme-driven membrane-targeted chimeric peptide for enhanced tumor photodynamic immunotherapy. ACS Nano 2019, 13, 11249.
11. Cheng Q#, Gao F#, Yu WY, Zou MZ, Ding XL, Li MJ, Cheng SX, Zhang XZ. Near-infrared-triggered a cascade of antitumor immune responses based on the integrated core-shell nanoparticle. Adv. Funct. Mater. 2020, 30,2000335.
12. Li MJ#, Gao F#, Huang QX, Feng J, Liu CJ, Gong SL, Zhang XZ. Natural killer cell-mimicking nanomaterial for overcoming the multidrug resistance of tumor via cascade catalysis. Sci. China Mater. 2023, 66, 1215.
13. Dai HM, Shen Q, Shao JJ, Wang WJ*, Gao F*, Dong XC*. Small molecular NIR-II fluorophores for cancer phototheranostics. The Innovation 2021, 2, 100082.
14. 张先正,高凡,郑迪威;用于高响应性抗肿瘤免疫疗法的HPV疫苗改性材料及其制备方法;2021.06.04;授权号:CN202010070249.5;(已授权)。